Always maximize your power strike and athletics, these two are your most important skills you got on foot.
The differences between 21/18 and 18/21 builds are very minimal. But it is a very solid build which fits well for most of the players. With time and train you can get to known which build is more suitable for your playing style, strenght, agile or balanced and the variables. They all got their advantages and weapons that fit with them (most of the people forgets, that the weapon which fits with the build is half the build).
To the two builds you posted here. I would go for the first one, the difference between 140 and 164 wpf is very low, but the difference between 4 iron flesh may get you survive one another hit.
Also with 7 athletics you can use long spear/pike very effectively or a big damage dealer weapon like awlpike or 4 hitting direction weapons like glaive & poleaxes.
Another thing, get a proper gear in use like armors with 40-50 body armor (i do use a 45 body armor most of the time).