I've had about 3 gens as a thrower, one as a horse thrower (before slot system, damn you slots). One does not throw with the reticule, one WILLS the projectile into your target. Occasionally your projectile flies off randomly into the corner of the reticule but for the most part they throw in the same place. You learn the tendencies of your throwing weapon of choice (axes for me) and they'll go where you want. THE RETICULE IS A LIE