It's a known issue that if you increase windows elements size through screen menu at 150% (in my case) you lose the mouse pointer on the game. It still show you on the screen but it's locked and you have no idea where is the real position of the pointer that is invisible. You can test around and sometimes it highlights the options of the menu but... is unplayable.
So I guess. Is there a way to fix it? Is related to WSE2? If I want to play crpg I have to down the scale of the elements windows show and on big screens is a ... disturbing issue. Thanks in advance.