My preferred 2h builds are:
18 str / 21 agi - 3 ironflesh, 6 power strike, 7 athletics, 7 weapon master
and
24 str / 15 agi - 5 ironflesh, 8 power strike, 5 athletics, 5 weapon master
The former(18/21) has the strength to use most everything and the mobility to better choose your fights. I think its especially great for newer players who are still in money making mode using lighter armors which lets your superior athletics shine through. The high wpf should give you a slightly larger counter-attacking window after blocking.
The latter(24/15) has great damage and a pretty good amount of hit points which will have synergy with heavier armor. Sometimes you can't avoid getting ganged but your athletics is plenty for solid footwork once engaged.