I love this game but wasnt able to play long since i died too fast
I got 17 hours on it already but only got myself like ~2-3 times into the city (without going to the lake)
Before i discovered trapping i always had botany and medic in my skills, trapping is also nice since you can get acces to the city without doing anything for hather ;) Also with botany you are able to make some kind of tea which boosts you immune system and can be selled for quite high (25$ per one drop)
Personally i dont like the disadvantages, the only one i took so far is the myopia since you can get rid of it with a surgery.(and since i got it for myself
)